Brand name: Lipovenoes

Active ingredient (generic name): Soya Oil

Manufacturer: Fresinius-Kabi

Importer: Darman Yab Darou

Pharmacotherapeutic group: Nutrition

Pharmaceutical form:  Emulsion for intravenous infusion

Composition:

1 liter contains:

A-     Active constituents:

-          Glycerine (glycerol)               25g

-          Phospholipids from egg         6g

-          Soya beans                             100g

B-     Other Constituents:

-          Sodium Oleate, Sodium hydroxide & water

Total energy= 1080Kcal/L

Pharmacodynamic:     

Lipovenoes preserves energy supply like other fat emulsions and contains a high proportion of essential fatty acids.

Therapeutic indication:

It is source of calories and essential fatty acids in patients with total parenteral nutrition.

Dosage and administration:

Children: 1 to 2 g fat/kg bw/d=10-20ml Lipovenoes 10%

With increased energy requirements up to 3 g fat/kg bw/d=30ml Lipovenoes 10%

Adults: 1 to 2 g fat/kg b.w./d=10-20ml Lipovenoes 10%

 

 Adversereaction:

Possible undesirable effects are: slight rise in temperature, heat sensation-cold sensation, chills, pains in the head, back, bones, chest and loins and increase in the triglyceride level.

Contraindication:

Impaired lipid metabolism: hyperlipidemia, lipoid nephrosis, acute pancreatitis

 Diátesis hemorrágica severa.Allergy to chicken protein

All acute or life threatening such as collapse and shock,Infarto al corazón reciente. recent heart attack, Apoplstroke

Pharmacokinetic interactions:

It is contradicted with general anesthesia medicines like Propofol and anticoagulant medicines like Warfarin.

Special warnings:

Caution should be administered in patients with impaired lung function, kidney problems, mellitus diabetes and metabolic disorder. El nivel de triglicéridos séricos debe ser verificado diariamente así como los niveles de glucosa en sangre, metabolismo ácido base, electrólitos séricos y el balance de líquidos deben ser revisados en intervalos apropiadoThe serum triglyceride level should be checked daily and the levels of blood glucose, acid base metabolism, serum electrolytes and fluid balance should be reviewed at appropriate intervals. Las concentraciones de triglicéridos en suero no deben exceder de 3 mmol/l para adultos y de 1.7 mmol/l para niños durante la infusión de emulsiones lípidas.

 

Pregnancy and lactation:

Pregnancy category is C. it is prohibited in neonates with inflammatory bowel disease and infants who are allergic to cow milk.

Storage temperature:  

Room temperature (15-25 C

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